Federal grants for nonprofits

Open federal funding opportunities for 501(c)(3) organizations, foundations, and community groups. Sorted by closing date, so the ones running out appear first.

763 open opportunities

Closes Oct 9, 2026Up to $300K

Development and Testing of a Multi-use Frameworks Playbook for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U01 Clinical Trial Not Allowed)

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes Nov 5, 2027Up to $1.5M

Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes Sep 29, 2027Up to $250K

Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline

Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline$0

Demonstration Projects for Whole-Person Health Models for Women Living with HIV in the South

Agency: Centers for Disease Control - NCHHSTP
Eligible locations: Nationwide

No stated deadline$0

DHQP Global NOFO

Agency: Centers for Disease Control - NCEZID
Eligible locations: Nationwide

No stated deadline$0 – $100K

Rural Health Network Development Planning Program

Agency: Health Resources and Services Administration
Eligible locations: Nationwide

No stated deadline

RNomics Outreach and Coordination (ROC) Center

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes Jan 7, 2027

NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadlineUp to $700K

Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes Dec 23, 2027

Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline

Research on System Support and Tools for Provider Training and Quality Monitoring for Suicide Preventive Care

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline

Mechanistic Exploration of Therapeutic Targets and Treatable Traits to Improve CNS Outcomes in People with HIV

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes May 7, 2027

Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes Jul 5, 2029

Research Opportunities in Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline$500K – $1.3M

National Foundation for the Centers for Disease Control and Prevention

Agency: Centers for Disease Control - OD
Eligible locations: Nationwide

Closes Jan 7, 2028

Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes Mar 5, 2027

Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline

Forecast to Publish a Funding Opportunity Announcement for Cancer Epidemiology Cohorts: Building the Next Generation of Research Cohorts (U01 Clinical Trial Not Allowed)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline

Clinical Trials in Organ Transplantation in Children and Adults

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline

Resource-Related Research Projects Cooperative Agreements in Aging and/or Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) Research

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline

Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

Agency: National Institutes of Health
Eligible locations: Nationwide

Closes Jan 1, 2099$375K

Annual Program Statement for U.S. Presentation at International Art Biennales

Agency: Bureau Of Educational and Cultural Affairs
Eligible locations: Nationwide

No stated deadline

NIDDK Disease Research and Translational Core Centers (P30 Clinical Trial Optional)

Agency: National Institutes of Health
Eligible locations: Nationwide

No stated deadline$250K – $500K

Improving Predictability of Food-Drug and Drug-Drug Interaction Risks by Utilizing In Vitro Simulated Gastrointestinal Dissolution Model for High-Risk Oral Drug Products (U01) Clinical Trial Optional

Agency: Food and Drug Administration
Eligible locations: Nationwide