Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed)
Program description
The purpose of this notice of funding opportunity (NOFO) is to support the advancement of systems-level understanding of the link between infectious pathogens and inflammatory pathways that result in predisposition, onset and progression of chronic diseases. The NOFO will stimulate integration of clinical and patient data, large-scale omics datasets, advanced Artificial Intelligence (AI) and computational modeling to prevent, treat, and mitigate the combined impact of chronic diseases, inflammation, and infections.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Past awards
Federal awards made under Assistance Listings 93.121 and 93.172 in FY2022–FY2026, from USAspending.gov.
- Awards made
- 2,039
- FY2022–FY2026
- Total awarded
- $2.1B
- FY2022–FY2026
- Typical award
- $429K
- Middle half $304.7K–$601.4K
- States & territories
- 52
- with at least one award
Typical award is the median of FY2026 awards under ALN 93.121, the largest listing on this grant; half of awards fell between the quartiles shown.
| Year | Total awarded | Awards |
|---|---|---|
| FY2022 | $650.7M | 416 |
| FY2023 | $536.4M | 452 |
| FY2024 | $421M | 437 |
| FY2025 | $263.5M | 339 |
| FY2026 | $234.1M | 395 |
Where awards went
Top states by dollars, all years on record
- California$1.4B · 547 awards
- Massachusetts$906M · 323 awards
- Washington$794.7M · 115 awards
- New York$576M · 321 awards
- Pennsylvania$480.1M · 253 awards
Source: USAspending.gov award records for these assistance listings, which also fund other opportunities. This is history, not a guarantee: future award sizes, counts and eligible recipients may differ. Exact total for FY2022–FY2026: $2,105,755,545.
Contact
NIAID OGAT (Division of Microbiology and Infectious Diseases) NIAIDOGAT@mail.nih.gov
NIAIDOGAT@mail.nih.gov