Immune Tolerance Network (UM1 Clinical Trial Required)

National Institutes of Health

Program description

The purpose of this notice of funding opportunity (NOFO) is to support applications to continue the Immune Tolerance Network (ITN). The primary objective of the Network is to develop tolerogenic therapies for immune-mediated disorders. The three main clinical areas of work are: 1) Allergic diseases and asthma; 2) Autoimmune diseases; and 3) Immune-mediated consequences of transplantation. The core functions of the ITN include designing, conducting, and sharing the results of clinical trials and performing integrated mechanistic studies.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Past awards

Federal awards made under Assistance Listing 93.855 in FY2022–FY2026, from USAspending.gov.

Awards made
8,660
FY2022–FY2026
Total awarded
$10.7B
FY2022–FY2026
Typical award
$313.5K
Middle half $158K–$713.2K
States & territories
52
with at least one award

Typical award is the median of FY2026 awards; half of awards fell between the quartiles shown.

Awarded by fiscal year
YearTotal awardedAwards
FY2022
$3.4B
1,510
FY2023
$2.5B
1,668
FY2024
$2.2B
1,689
FY2025
$1.5B
1,577
FY2026
$1.1B
2,216

Where awards went

Top states by dollars, all years on record

  1. California$5.2B · 1,808 awards
  2. Massachusetts$3.7B · 1,329 awards
  3. New York$3.3B · 1,305 awards
  4. Washington$3.2B · 617 awards
  5. North Carolina$3.1B · 669 awards

Source: USAspending.gov award records for this assistance listing, which can fund more than one opportunity. This is history, not a guarantee: future award sizes, counts and eligible recipients may differ. Exact total for FY2022–FY2026: $10,718,465,457.

Contact

Division of Allergy, Immunology and Transplantation ITN_UM1@mail.nih.gov

ITN_UM1@mail.nih.gov